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Pathogenic autoantibodies are routinely generated during the response to foreign antigen: a paradigm for autoimmune disease.
The immune system's ability to distinguish self and nonself is essential for both host defense against foreign agents and protection of self-antigens from autoimmune destruction. Such discrimination is complicated by extensive structural homology shared between foreign and self antigens. One hy...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1996
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC39902/ https://ncbi.nlm.nih.gov/pubmed/8700878 |
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