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Concerns about unapproved meningococcal vaccination for eculizumab therapy in Japan

An orphan medicinal product, eculizumab is approved in Japan and globally for treating paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome. Eculizumab therapy can cause late complement pathway deficiencies that predispose patients to meningococcal infections. Although meningoc...

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Dades bibliogràfiques
Autors principals: Tanimoto, Tetsuya, Kusumi, Eiji, Hosoda, Kazutaka, Kouno, Kaduki, Hamaki, Tamae, Kami, Masahiro
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990028/
https://ncbi.nlm.nih.gov/pubmed/24716834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-9-48
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