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Concerns about unapproved meningococcal vaccination for eculizumab therapy in Japan

An orphan medicinal product, eculizumab is approved in Japan and globally for treating paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome. Eculizumab therapy can cause late complement pathway deficiencies that predispose patients to meningococcal infections. Although meningoc...

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Detalhes bibliográficos
Main Authors: Tanimoto, Tetsuya, Kusumi, Eiji, Hosoda, Kazutaka, Kouno, Kaduki, Hamaki, Tamae, Kami, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990028/
https://ncbi.nlm.nih.gov/pubmed/24716834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-9-48
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