Antiangiogenic therapy of transgenic mice impairs de novo tumor growth.

Angiogenesis is activated during multistage tumorigenesis prior to the emergence of solid tumors. Using a transgenic mouse model, we have tested the proposition that treatment with angiogenesis inhibitors can inhibit the progression of tumorigenesis after the switch to the angiogenic phenotype. In t...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Parangi, S, O'Reilly, M, Christofori, G, Holmgren, L, Grosfeld, J, Folkman, J, Hanahan, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39899/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8700875/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.5.2002
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