Circulating human rotavirus specific CD4 T cells identified with a class II tetramer express the intestinal homing receptors α4β7 and CCR9

Using a consensus epitope prediction approach, three rotavirus (RV) peptides that induce cytokine secretion by CD4 T cells from healthy volunteers were identified. The peptides were shown to bind HLA-DRB1*0101 and then used to generate MHC II tetramers. RV specific T cell lines specific for one of t...

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Main Authors: Parra, Miguel, Herrera, Daniel, Calvo-Calle, J. Mauricio, Stern, Lawrence J., Parra-López, Carlos A., Butcher, Eugene, Franco, Manuel, Angel, Juana
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989888/
https://ncbi.nlm.nih.gov/pubmed/24606696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.01.014
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