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Intermittent hypoxia-induced endothelial barrier dysfunction requires ROS-dependent MAP kinase activation

The objective of the present study was to determine the impact of simulated apnea with intermittent hypoxia (IH) on endothelial barrier function and assess the underlying mechanism(s). Experiments were performed on human lung microvascular endothelial cells exposed to IH-consisting alternating cycle...

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Detalhes bibliográficos
Main Authors: Makarenko, Vladislav V., Usatyuk, Peter V., Yuan, Guoxiang, Lee, May M., Nanduri, Jayasri, Natarajan, Viswanathan, Kumar, Ganesh K., Prabhakar, Nanduri R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989715/
https://ncbi.nlm.nih.gov/pubmed/24477234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00313.2013
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