Remote conditioning or erythropoietin before surgery primes kidneys to clear ischemia-reperfusion-damaged cells: a renoprotective mechanism?

Acute kidney injury is common, serious with no specific treatment. Ischemia-reperfusion is a common cause of acute kidney injury (AKI). Clinical trials suggest that preoperative erythropoietin (EPO) or remote ischemic preconditioning may have a renoprotective effect. Using a porcine model of warm is...

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Main Authors: Gardner, David S., Welham, Simon J. M., Dunford, Louise J., McCulloch, Thomas A., Hodi, Zsolt, Sleeman, Philippa, O'Sullivan, Saoirse, Devonald, Mark A. J.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2014
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989632/
https://ncbi.nlm.nih.gov/pubmed/24523383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00576.2013
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