Requirement for highly efficient pre-mRNA splicing during Drosophila early embryonic development

Drosophila syncytial nuclear divisions limit transcription unit size of early zygotic genes. As mitosis inhibits not only transcription, but also pre-mRNA splicing, we reasoned that constraints on splicing were likely to exist in the early embryo, being splicing avoidance a possible explanation why...

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Bibliographic Details
Main Authors: Guilgur, Leonardo Gastón, Prudêncio, Pedro, Sobral, Daniel, Liszekova, Denisa, Rosa, André, Martinho, Rui Gonçalo
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2014
Subjects:
Developmental Biology and Stem Cells
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989599/
https://ncbi.nlm.nih.gov/pubmed/24755291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02181
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