Methamphetamine down-regulates striatal glutamate receptors via diverse epigenetic mechanisms

BACKGROUND: Chronic methamphetamine (METH) exposure causes neuroadaptations at glutamatergic synapses. METHODS: To identify the METH-induced epigenetic underpinnings of these adaptations in the brain, we injected increasing METH doses to rats for two weeks and measured striatal glutamate receptor ex...

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Detalhes bibliográficos
Main Authors: Jayanthi, Subramaniam, McCoy, Michael T., Chen, Billy, Britt, Jonathan, Kourrich, Saïd, Yau, Hau-Jie, Ladenheim, Bruce, Krasnova, Irina N., Bonci, Antonello, Cadet, Jean Lud
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989474/
https://ncbi.nlm.nih.gov/pubmed/24239129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2013.09.034
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