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Electrophysiological characterization of spinal neuron sensitization by elevated calcium channel alpha-2-delta-1 subunit protein

BACKGROUND: Voltage-gated calcium channel α(2)δ(1) subunit is the binding site for gabapentin, an effective drug in controlling neuropathic pain states including thermal hyperalgesia. Hyperalgesia to noxious thermal stimuli in both spinal-nerve-ligated (SNL) and voltage-gated calcium channel α(2)δ(1...

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Detalhes bibliográficos
Main Authors: Zhou, Chunyi, Luo, Z. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989413/
https://ncbi.nlm.nih.gov/pubmed/24151064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/j.1532-2149.2013.00416.x
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