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Association of CASQ2 Polymorphisms With Sudden Cardiac Arrest and Heart Failure in Patients with Coronary Artery Disease

BACKGROUND: Abnormal calcium handling plays a crucial role in arrhythmias, sudden cardiac arrest (SCA), and congestive heart failure (CHF). Calsequestrin 2 (CASQ2) mutations affect calcium release and initiate malignant ventricular arrhythmias (VA) and SCA syndromes. Common single nucleotide polymor...

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Hlavní autoři: Refaat, Marwan M., Aouizerat, Bradley E., Pullinger, Clive R., Malloy, Mary, Kane, John, Tseng, Zian H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989347/
https://ncbi.nlm.nih.gov/pubmed/24444446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2014.01.015
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