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Gel Formation in Protein Amyloid Aggregation: A Physical Mechanism for Cytotoxicity
Amyloid fibers are associated with disease but have little chemical reactivity. We investigated the formation and structure of amyloids to identify potential mechanisms for their pathogenic effects. We incubated lysozyme 20 mg/ml at 55C and pH 2.5 in a glycine-HCl buffer and prepared slides on mica...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989237/ https://ncbi.nlm.nih.gov/pubmed/24740416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094789 |
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