Neutrophils Recruited by IL-22 in Peripheral Tissues Function as TRAIL-Dependent Antiviral Effectors against MCMV

During primary infection, murine cytomegalovirus (MCMV) spreads systemically, resulting in virus replication and pathology in multiple organs. This disseminated infection is ultimately controlled, but the underlying immune defense mechanisms are unclear. Investigating the role of the cytokine IL-22...

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Main Authors: Stacey, Maria A., Marsden, Morgan, Pham N, Tu Anh, Clare, Simon, Dolton, Garry, Stack, Gabrielle, Jones, Emma, Klenerman, Paul, Gallimore, Awen M., Taylor, Philip R., Snelgrove, Robert J., Lawley, Trevor D., Dougan, Gordon, Benedict, Chris A., Jones, Simon A., Wilkinson, Gavin W.G., Humphreys, Ian R.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989063/
https://ncbi.nlm.nih.gov/pubmed/24721575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.03.003
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