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Molecular Mechanism of Antibody-Mediated Activation of β-galactosidase
Binding of a single-chain Fv antibody to Escherichia coli β-galactosidase (β-gal) is known to stabilize the enzyme and activate several inactive point mutants, historically called antibody-mediated enzyme formation mutants. To understand the nature of this activation, we have determined by electron...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3988998/ https://ncbi.nlm.nih.gov/pubmed/24613486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.01.011 |
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