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The gut hormone glucagon-like peptide-1 produced in brain: is this physiologically relevant?

Glucagon-like peptide-1 (GLP-1) is both a peripherally expressed incretin and a centrally active neuropeptide. Brain derived GLP-1, produced in preproglucagon (PPG) neurons located in the nucleus of the solitary tract (NTS) and projecting to numerous brain regions, is ideally placed to activate cent...

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Detalhes bibliográficos
Main Authors: Trapp, Stefan, Richards, James E
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988995/
https://ncbi.nlm.nih.gov/pubmed/24075717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2013.09.006
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