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Replication Origin Selection Regulates the Distribution of Meiotic Recombination

The program of DNA replication, defined by the temporal and spatial pattern of origin activation, is altered during development and in cancers. However, whether changes in origin usage play a role in regulating specific biological processes remains unknown. We investigated the consequences of modify...

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Bibliographic Details
Main Authors: Wu, Pei-Yun Jenny, Nurse, Paul
Format: Artigo
Language:Inglês
Published: Cell Press 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988929/
https://ncbi.nlm.nih.gov/pubmed/24560273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.01.022
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