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Phosphoregulation of Ire1 RNase splicing activity

Ire1 is activated in response to accumulation of misfolded proteins within the endoplasmic reticulum as part of the unfolded protein response (UPR). It is a unique enzyme, possessing both kinase and RNase activity that is required for specific splicing of Xbp1 mRNA leading to UPR activation. How pho...

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Detaylı Bibliyografya
Asıl Yazarlar: Prischi, Filippo, Nowak, Piotr R., Carrara, Marta, Ali, Maruf M. U.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Pub. Group 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988810/
https://ncbi.nlm.nih.gov/pubmed/24704861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4554
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