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The effect of low and high plasma levels of insulin-like growth factor-1 (IGF-1) on the morphology of major organs: studies of Laron dwarf and bovine growth hormone transgenic (bGHTg) mice

It is well known that somatotrophic/insulin signaling affects lifespan in experimental animals. To study the effects of insulin-like growth factor-1 (IGF-1) plasma level on the morphology of major organs, we analyzed lung, heart, liver, kidney, bone marrow, and spleen isolated from 2-year-old growth...

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Detalhes bibliográficos
Main Authors: Piotrowska, Katarzyna, Borkowska, Sylwia J., Wiszniewska, Barbara, Laszczyńska, Maria, Słuczanowska-Głąbowska, Sylwia, Havens, Aaron M., Kopchick, John J., Bartke, Andrzej, Taichman, Russel S., Kucia, Magda, Ratajczak, Mariusz Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988530/
https://ncbi.nlm.nih.gov/pubmed/23613169
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