B and T Lymphocyte Attenuator Down-regulation by HIV-1 Depends on Type I Interferon and Contributes to T-Cell Hyperactivation

Background. Nonspecific T-cell hyperactivation is the main driving force for human immunodeficiency virus (HIV)–1 disease progression, but the reasons why the excess immune response is not properly shut off are poorly defined. Methods. Eighty-five HIV-1–infected individuals were enrolled to characte...

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Detalhes bibliográficos
Main Authors: Zhang, Zheng, Xu, Xiangsheng, Lu, Jiyun, Zhang, Shuye, Gu, Lanlan, Fu, Junliang, Jin, Lei, Li, Haiying, Zhao, Min, Zhang, Jiyuan, Wu, Hao, Su, Lishan, Fu, Yang-Xin, Wang, Fu-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988446/
https://ncbi.nlm.nih.gov/pubmed/21592997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir165
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