Role of pancreatic stellate cells in chemoresistance in pancreatic cancer

Pancreatic cancer is highly chemoresistant. A major contributing factor is the characteristic extensive stromal or fibrotic reaction, which comprises up to 90% of the tumor volume. Over the last decade there has been intensive research into the role of the pro-fibrogenic pancreatic stellate cells (P...

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Detalles Bibliográficos
Autores principales: McCarroll, Joshua A., Naim, Stephanie, Sharbeen, George, Russia, Nelson, Lee, Julia, Kavallaris, Maria, Goldstein, David, Phillips, Phoebe A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2014
Materias:
Physiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988387/
https://ncbi.nlm.nih.gov/pubmed/24782785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00141
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