MITF E318K’s effect on melanoma risk independent of, but modified by, other risk factors

A rare germline variant in the MITF (microphthalmia-associated transcription factor) gene, E318K, has been reported as associated with melanoma. We confirmed its independent association with melanoma (odds ratio (OR) 1.7, 95% Confidence Interval (CI) = 1.1, 2.7, p = 0.03); adjusted for age, sex, cen...

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Detalhes bibliográficos
Main Authors: Berwick, Marianne, MacArthur, Jamie, Orlow, Irene, Kanetsky, Peter, Begg, Colin B., Luo, Li, Reiner, Anne, Sharma, Ajay, Armstrong, Bruce K., Kricker, Anne, Cust, Anne E., Marrett, Loraine D., Gruber, Stephen B., Anton-Culver, Hoda, Zanetti, Roberto, Rosso, Stefano, Gallagher, Richard P., Dwyer, Terrance, Venn, Alison, Busam, Klaus, From, Lynn, White, Kirsten, Thomas, Nancy E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988207/
https://ncbi.nlm.nih.gov/pubmed/24406078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12215
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