Multivalent Presentation of MPL by Porous Silicon Microparticles Favors T Helper 1 Polarization Enhancing the Anti-Tumor Efficacy of Doxorubicin Nanoliposomes

Porous silicon (pSi) microparticles, in diverse sizes and shapes, can be functionalized to present pathogen-associated molecular patterns that activate dendritic cells. Intraperitoneal injection of MPL-adsorbed pSi microparticles, in contrast to free MPL, resulted in the induction of local inflammat...

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Autori principali: Meraz, Ismail M., Hearnden, Claire H., Liu, Xuewu, Yang, Marie, Williams, Laura, Savage, David J., Gu, Jianhua, Rhudy, Jessica R., Yokoi, Kenji, Lavelle, Ed C., Serda, Rita E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988134/
https://ncbi.nlm.nih.gov/pubmed/24736547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094703
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