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Lysosomal Function Is Involved in 17β-Estradiol-Induced Estrogen Receptor α Degradation and Cell Proliferation

The homeostatic control of the cellular proteome steady-state is dependent either on the 26S proteasome activity or on the lysosome function. The sex hormone 17β-estradiol (E2) controls a plethora of biological functions by binding to the estrogen receptor α (ERα), which is both a nuclear ligand-act...

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Bibliografiska uppgifter
Huvudupphovsmän: Totta, Pierangela, Pesiri, Valeria, Marino, Maria, Acconcia, Filippo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988130/
https://ncbi.nlm.nih.gov/pubmed/24736371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094880
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