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JNK signaling is needed to tolerate chromosomal instability
Chromosomal instability (CIN), as a common feature of tumors, represents a potential therapeutic target if ways can be found to specifically cause apoptosis in unstably dividing cells. We have previously shown that if signaling through the JNK pathway is reduced, apoptosis is triggered in models of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3988119/ https://ncbi.nlm.nih.gov/pubmed/24335260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27484 |
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