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Automated Protein Turnover Calculations from (15)N Partial Metabolic Labeling LC/MS Shotgun Proteomics Data

Protein turnover is a well-controlled process in which polypeptides are constantly being degraded and subsequently replaced with newly synthesized copies. Extraction of composite spectral envelopes from complex LC/MS shotgun proteomics data can be a challenging task, due to the inherent complexity o...

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Autors principals: Lyon, David, Castillejo, Maria Angeles, Staudinger, Christiana, Weckwerth, Wolfram, Wienkoop, Stefanie, Egelhofer, Volker
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988089/
https://ncbi.nlm.nih.gov/pubmed/24736476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094692
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