The HIV Matrix Protein p17 Promotes the Activation of Human Hepatic Stellate Cells through Interactions with CXCR2 and Syndecan-2

BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) p17 is a matrix protein involved in virus life's cycle. CXCR2 and Syndecan-2, the two major coreceptors for the p17 protein, are expressed in hepatic stellate cells (HSCs), a key cell type involved in matrix deposition in liver fibroti...

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Detalhes bibliográficos
Main Authors: Renga, Barbara, Francisci, Daniela, Schiaroli, Elisabetta, Carino, Adriana, Cipriani, Sabrina, D'Amore, Claudio, Sidoni, Angelo, Sordo, Rachele Del, Ferri, Ivana, Lucattelli, Monica, Lunghi, Benedetta, Baldelli, Franco, Fiorucci, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988079/
https://ncbi.nlm.nih.gov/pubmed/24736615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094798
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