Pou4f1 and Pou4f2 Are Dispensable for the Long-Term Survival of Adult Retinal Ganglion Cells in Mice

PURPOSE: To investigate the role of Pou4f1 and Pou4f2 in the survival of adult retinal ganglion cells (RGCs). METHODS: Conditional alleles of Pou4f1 and Pou4f2 were generated (Pou4f1(loxP) and Pou4f2(loxP) respectively) for the removal of Pou4f1 and Pou4f2 in adult retinas. A tamoxifen-inducible Cre...

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Detalhes bibliográficos
Main Authors: Huang, Liang, Hu, Fang, Xie, Xiaoling, Harder, Jeffery, Fernandes, Kimberly, Zeng, Xiang-yun, Libby, Richard, Gan, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988073/
https://ncbi.nlm.nih.gov/pubmed/24736625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094173
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