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Endogenous Positive Allosteric Modulation of GABA(A) Receptors by Diazepam binding inhibitor
Benzodiazepines (BZs) allosterically modulate γ-aminobutyric acid type-A receptors (GABA(A)Rs) to increase inhibitory synaptic strength. Diazepam binding inhibitor (DBI) protein is a BZ site ligand expressed endogenously in the brain, but functional evidence for BZ-mimicking positive modulatory acti...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3987987/ https://ncbi.nlm.nih.gov/pubmed/23727119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.04.026 |
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