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The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

Precise control of organ size is crucial during animal development and regeneration. In Drosophila and mammals, studies over the past decade have uncovered a critical role for the Hippo tumour-suppressor pathway in the regulation of organ size. Dysregulation of this pathway leads to massive overgrow...

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Bibliographic Details
Main Authors: Zhao, Bin, Tumaneng, Karen, Guan, Kun-Liang
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987945/
https://ncbi.nlm.nih.gov/pubmed/21808241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2303
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