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The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis

BACKGROUND: The nootropic neuroprotective peptide Semax (Met-Glu-His-Phe-Pro-Gly-Pro) has proved efficient in the therapy of brain stroke; however, the molecular mechanisms underlying its action remain obscure. Our genome-wide study was designed to investigate the response of the transcriptome of is...

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Detalhes bibliográficos
Main Authors: Medvedeva, Ekaterina V, Dmitrieva, Veronika G, Povarova, Oksana V, Limborska, Svetlana A, Skvortsova, Veronika I, Myasoedov, Nikolay F, Dergunova, Lyudmila V
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987924/
https://ncbi.nlm.nih.gov/pubmed/24661604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-228
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