HEPBURN - investigating the efficacy and safety of nebulized heparin versus placebo in burn patients with inhalation trauma: study protocol for a multi-center randomized controlled trial

BACKGROUND: Pulmonary coagulopathy is a hallmark of lung injury following inhalation trauma. Locally applied heparin attenuates lung injury in animal models of smoke inhalation. Whether local treatment with heparin benefits patients with inhalation trauma is uncertain. The present trial aims at comp...

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Bibliografiska uppgifter
Huvudupphovsmän: Glas, Gerie J, Muller, Johannes, Binnekade, Jan M, Cleffken, Berry, Colpaert, Kirsten, Dixon, Barry, Juffermans, Nicole P, Knape, Paul, Levi, Marcel M, Loef, Bert G, Mackie, David P, Malbrain, Manu, Schultz, Marcus J, van der Sluijs, Koenraad F
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2014
Ämnen:
Study Protocol
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987885/
https://ncbi.nlm.nih.gov/pubmed/24661817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-15-91
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