HEPBURN - investigating the efficacy and safety of nebulized heparin versus placebo in burn patients with inhalation trauma: study protocol for a multi-center randomized controlled trial

BACKGROUND: Pulmonary coagulopathy is a hallmark of lung injury following inhalation trauma. Locally applied heparin attenuates lung injury in animal models of smoke inhalation. Whether local treatment with heparin benefits patients with inhalation trauma is uncertain. The present trial aims at comp...

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Detalhes bibliográficos
Main Authors: Glas, Gerie J, Muller, Johannes, Binnekade, Jan M, Cleffken, Berry, Colpaert, Kirsten, Dixon, Barry, Juffermans, Nicole P, Knape, Paul, Levi, Marcel M, Loef, Bert G, Mackie, David P, Malbrain, Manu, Schultz, Marcus J, van der Sluijs, Koenraad F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987885/
https://ncbi.nlm.nih.gov/pubmed/24661817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-15-91
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