HEPBURN - investigating the efficacy and safety of nebulized heparin versus placebo in burn patients with inhalation trauma: study protocol for a multi-center randomized controlled trial

BACKGROUND: Pulmonary coagulopathy is a hallmark of lung injury following inhalation trauma. Locally applied heparin attenuates lung injury in animal models of smoke inhalation. Whether local treatment with heparin benefits patients with inhalation trauma is uncertain. The present trial aims at comp...

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Hlavní autoři: Glas, Gerie J, Muller, Johannes, Binnekade, Jan M, Cleffken, Berry, Colpaert, Kirsten, Dixon, Barry, Juffermans, Nicole P, Knape, Paul, Levi, Marcel M, Loef, Bert G, Mackie, David P, Malbrain, Manu, Schultz, Marcus J, van der Sluijs, Koenraad F
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Study Protocol
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987885/
https://ncbi.nlm.nih.gov/pubmed/24661817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-15-91
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