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Transcriptome analysis identifies Bacillus anthracis genes that respond to CO(2) through an AtxA-dependent mechanism

BACKGROUND: Upon infection of a mammalian host, Bacillus anthracis responds to host cues, and particularly to elevated temperature (37°C) and bicarbonate/CO(2) concentrations, with increased expression of virulence factors that include the anthrax toxins and extracellular capsular layer. This respon...

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Bibliographic Details
Main Authors: McKenzie, Andrew T, Pomerantsev, Andrei P, Sastalla, Inka, Martens, Craig, Ricklefs, Stacy M, Virtaneva, Kimmo, Anzick, Sarah, Porcella, Stephen F, Leppla, Stephen H
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987803/
https://ncbi.nlm.nih.gov/pubmed/24661624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-229
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