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Etv2 rescues Flk1 mutant embryoid bodies

Independent mouse knockouts of Etv2 and Flk1 are embryonic lethal and lack hematopoietic and endothelial lineages. We previously reported that Flk1 activates Etv2 in the initiation of hematopoiesis and vasculogenesis. However, Flk1 and its ligand VEGF are expressed throughout development, from E7.0...

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Detalhes bibliográficos
Main Authors: Rasmussen, Tara L., Martin, Cindy M., Walter, Camille A., Shi, Xiaozhong, Perlingeiro, Rita, Koyano-Nakagawa, Naoko, Garry, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987665/
https://ncbi.nlm.nih.gov/pubmed/23606617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22396
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