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Silibinin inhibits accumulation of myeloid-derived suppressor cells and tumor growth of murine breast cancer

Myeloid-derived suppressor cells (MDSC)s increase in blood and accumulate in the tumor microenvironment of tumor-bearing animals, contributing to immune suppression in cancer. Silibinin, a natural flavonoid from the seeds of milk thistle, has been developed as an anti-inflammatory agent and supporti...

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Detalhes bibliográficos
Main Authors: Forghani, Parvin, Khorramizadeh, Mohammad R, Waller, Edmund K
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987072/
https://ncbi.nlm.nih.gov/pubmed/24574320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.186
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