Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury

BACKGROUND: Traumatic brain injury (TBI) initiates a neuroinflammatory cascade that contributes to substantial neuronal damage and behavioral impairment, and Toll-like receptor 4 (TLR4) is an important mediator of thiscascade. In the current study, we tested the hypothesis that curcumin, a phytochem...

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Bibliographische Detailangaben
Hauptverfasser: Zhu, Hai-tao, Bian, Chen, Yuan, Ji-chao, Chu, Wei-hua, Xiang, Xin, Chen, Fei, Wang, Cheng-shi, Feng, Hua, Lin, Jiang-kai
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986937/
https://ncbi.nlm.nih.gov/pubmed/24669820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-59
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