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Visualization of angiogenesis during cancer development in the polyoma middle T breast cancer model: molecular imaging with (R)-[(11)C]PAQ

BACKGROUND: Vascular endothelial growth factor receptor 2 (VEGFR2) is a crucial mediator of tumour angiogenesis. High expression levels of the receptor have been correlated to poor prognosis in cancer patients. Reliable imaging biomarkers for stratifying patients for anti-angiogenic therapy could th...

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Detalhes bibliográficos
Main Authors: Samén, Erik, Lu, Li, Mulder, Jan, Thorell, Jan-Olov, Damberg, Peter, Tegnebratt, Tetyana, Holmgren, Lars, Rundqvist, Helene, Stone-Elander, Sharon
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986910/
https://ncbi.nlm.nih.gov/pubmed/24670127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-219X-4-17
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