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Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis
Hairless (HR) is a nuclear protein with co-repressor activity that is highly expressed in the skin and hair follicle. Mutations in Hairless lead to hair loss accompanied by the appearance of papules (atrichia with papular lesions) and similar phenotypes appear when the key polyamine enzymes ornithin...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3986865/ https://ncbi.nlm.nih.gov/pubmed/24079733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.12228 |
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