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Ganglioside deficiency causes inflammation and neurodegeneration via the activation of complement system in the spinal cord
BACKGROUND: Gangliosides, sialic acid-containing glycosphingolipids, are highly expressed in nervous systems of vertebrates and have been considered to be involved in the development, differentiation, and function of nervous tissues. Recent studies with gene-engineered animals have revealed that the...
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Huvudupphovsmän: | , , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
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BioMed Central
2014
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3986855/ https://ncbi.nlm.nih.gov/pubmed/24673754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-61 |
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