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Regulation of Src trafficking and activation by the endocytic regulatory proteins MICAL-L1 and EHD1

Localization of the non-receptor tyrosine kinase Src to the cell periphery is required for its activation and to mediate focal adhesion turnover, cell spreading and migration. Inactive Src localizes to a perinuclear compartment and the movement of Src to the plasma membrane is mediated by endocytic...

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Autores principales: Reinecke, James B., Katafiasz, Dawn, Naslavsky, Naava, Caplan, Steve
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986674/
https://ncbi.nlm.nih.gov/pubmed/24481818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.133892
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