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Regulation of Src trafficking and activation by the endocytic regulatory proteins MICAL-L1 and EHD1
Localization of the non-receptor tyrosine kinase Src to the cell periphery is required for its activation and to mediate focal adhesion turnover, cell spreading and migration. Inactive Src localizes to a perinuclear compartment and the movement of Src to the plasma membrane is mediated by endocytic...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Company of Biologists
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3986674/ https://ncbi.nlm.nih.gov/pubmed/24481818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.133892 |
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