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Activation of the omega-3 fatty acid receptor GPR120 mediates anti-inflammatory actions in immortalized hypothalamic neurons

BACKGROUND: Overnutrition and the ensuing hypothalamic inflammation is a major perpetuating factor in the development of metabolic diseases, such as obesity and diabetes. Inflamed neurons of the CNS fail to properly regulate energy homeostasis leading to pathogenic changes in glucose handling, feedi...

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Détails bibliographiques
Auteurs principaux: Wellhauser, Leigh, Belsham, Denise D
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986641/
https://ncbi.nlm.nih.gov/pubmed/24674717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-60
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