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Cellular aging, destabilization, and cancer.

Three major characteristics of aging in animals are a slowdown of cell proliferation, an increase in residual bodies associated with age pigments, and a marked increase in the likelihood of neoplastic transformation. The 28 L subline of the NIH 3T3 line of mouse embryo fibroblasts exhibits all these...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Rubin, H, Chow, M, Yao, A
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1996
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39866/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8700843/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.5.1825
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