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Identification of Multipotent Progenitors that Emerge Prior to Hematopoietic Stem Cells in Embryonic Development

Hematopoiesis in the embryo proceeds in a series of waves, with primitive erythroid-biased waves succeeded by definitive waves, within which the properties of hematopoietic stem cells (multilineage potential, self-renewal, and engraftability) gradually arise. Whereas self-renewal and engraftability...

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Autori principali: Inlay, Matthew A., Serwold, Thomas, Mosley, Adriane, Fathman, John W., Dimov, Ivan K., Seita, Jun, Weissman, Irving L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986503/
https://ncbi.nlm.nih.gov/pubmed/24749071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.02.001
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