Intracellular activity of tedizolid phosphate and ACH-702 versus Mycobacterium tuberculosis infected macrophages

BACKGROUND: Due to the emergency of multidrug-resistant strains of Mycobacterium tuberculosis, is necessary the evaluation of new compounds. FINDINGS: Tedizolid, a novel oxazolidinone, and ACH-702, a new isothiazoloquinolone, were tested against M. tuberculosis infected THP-1 macrophages. These two...

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Bibliographic Details
Main Authors: Molina-Torres, Carmen A, Barba-Marines, Alejandra, Valles-Guerra, Orestes, Ocampo-Candiani, Jorge, Cavazos-Rocha, Norma, Pucci, Michael J, Castro-Garza, Jorge, Vera-Cabrera, Lucio
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Short Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986449/
https://ncbi.nlm.nih.gov/pubmed/24708819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-0711-13-13
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