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Effects of human insulin and insulin aspart preparations on levels of IGF-I, IGFBPs and IGF bioactivity in patients with type 1 diabetes

BACKGROUND: Insulin aspart (IAsp) and its biphasic preparations BIAsp50 and BIAsp70 (containing 50% and 70% IAsp, respectively) have distinct glucose-lowering properties as compared to human insulin (HI). We investigated whether this affected the circulating IGF-system which depends on the hepatic i...

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Autors principals: Ma, Zhulin, Christiansen, Jens Sandahl, Laursen, Torben, Wu, Chunsen, Lauritzen, Torsten, Parkner, Tina, Frystyk, Jan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986432/
https://ncbi.nlm.nih.gov/pubmed/24725803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6823-14-35
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