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Prolonged Administration of Azacitidine With or Without Entinostat for Myelodysplastic Syndrome and Acute Myeloid Leukemia With Myelodysplasia-Related Changes: Results of the US Leukemia Intergroup Trial E1905

PURPOSE: Although azacitidine (AZA) improves survival in patients with high-risk myelodysplastic syndrome, the overall response remains approximately 50%. Entinostat is a histone deacetylase inhibitor that has been combined with AZA with significant clinical activity in a previous phase I dose findi...

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Bibliografiske detaljer
Main Authors: Prebet, Thomas, Sun, Zhuoxin, Figueroa, Maria E., Ketterling, Rhett, Melnick, Ari, Greenberg, Peter L., Herman, James, Juckett, Mark, Smith, Mitchell R., Malick, Lisa, Paietta, Elisabeth, Czader, Magdalena, Litzow, Mark, Gabrilove, Janice, Erba, Harry P., Gore, Steven D., Tallman, Martin S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Clinical Oncology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986386/
https://ncbi.nlm.nih.gov/pubmed/24663049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2013.50.3102
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