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Development of nucleic acid vaccines: use of self-amplifying RNA in lipid nanoparticles

Self-amplifying RNA or RNA replicon is a form of nucleic acid-based vaccine derived from either positive-strand or negative-strand RNA viruses. The gene sequences encoding structural proteins in these RNA viruses are replaced by mRNA encoding antigens of interest as well as by RNA polymerase for rep...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Rodríguez-Gascón, Alicia, del Pozo-Rodríguez, Ana, Solinís, María Ángeles
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Dove Medical Press 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986288/
https://ncbi.nlm.nih.gov/pubmed/24748793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S39810
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