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Homolog detection using global sequence properties suggests an alternate view of structural encoding in protein sequences

We show that a Fourier-based sequence distance function is able to identify structural homologs of target sequences with high accuracy. It is shown that Fourier distances correlate very strongly with independently determined structural distances between molecules, a property of the method that is no...

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Bibliografiske detaljer
Main Authors: Scheraga, Harold A., Rackovsky, S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986189/
https://ncbi.nlm.nih.gov/pubmed/24706836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403599111
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