Small cationic antimicrobial peptides delocalize peripheral membrane proteins

Short antimicrobial peptides rich in arginine (R) and tryptophan (W) interact with membranes. To learn how this interaction leads to bacterial death, we characterized the effects of the minimal pharmacophore RWRWRW-NH(2). A ruthenium-substituted derivative of this peptide localized to the membrane i...

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Detalhes bibliográficos
Main Authors: Wenzel, Michaela, Chiriac, Alina Iulia, Otto, Andreas, Zweytick, Dagmar, May, Caroline, Schumacher, Catherine, Gust, Ronald, Albada, H. Bauke, Penkova, Maya, Krämer, Ute, Erdmann, Ralf, Metzler-Nolte, Nils, Straus, Suzana K., Bremer, Erhard, Becher, Dörte, Brötz-Oesterhelt, Heike, Sahl, Hans-Georg, Bandow, Julia Elisabeth
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986158/
https://ncbi.nlm.nih.gov/pubmed/24706874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319900111
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