A Kinase-Independent Activity of Cdk9 Modulates Glucocorticoid Receptor-Mediated Gene Induction

[Image: see text] A gene induction competition assay has recently uncovered new inhibitory activities of two transcriptional cofactors, NELF-A and NELF-B, in glucocorticoid-regulated transactivation. NELF-A and -B are also components of the NELF complex, which participates in RNA polymerase II pausi...

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Bibliographic Details
Main Authors: Zhu, Rong, Lu, Xinping, Pradhan, Madhumita, Armstrong, Stephen P., Storchan, Geoffrey B., Chow, Carson C., Simons, S. Stoney
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985961/
https://ncbi.nlm.nih.gov/pubmed/24559102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5000178
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