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Developing New Isotope-Coded Mass Spectrometry-Cleavable Cross-Linkers for Elucidating Protein Structures

[Image: see text] Structural characterization of protein complexes is essential for the understanding of their function and regulation. However, it remains challenging due to limitations in existing tools. With recent technological improvements, cross-linking mass spectrometry (XL-MS) has become a p...

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Detalhes bibliográficos
Main Authors: Yu, Clinton, Kandur, Wynne, Kao, Athit, Rychnovsky, Scott, Huang, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985771/
https://ncbi.nlm.nih.gov/pubmed/24471733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac403636b
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